Introducing ComfyCell
The all-in-one solution for scalable & controllable cell therapy manufacturing, consisting of a proprietary bionic bioreactor vessel package & compatible controller unit.
Our Technical Breakthrough
Single Use Bioreactor
- Closed-system single use vessel in 300 mL to 10 L
- In-process control with temperature, DO & pH sensors
- Integrated BioThrust Membrane Stirrer
Reusable Bioreactor
- Autoclavable glass vessel in 250 mL to 10 L
- In-process control with temperature, DO & pH sensors
- Replaceable BioThrust Membrane Stirrer
Bioreactor Controller
- Modern touchscreen interface for process control & monitoring
- Configurable process profiles
- Small footprint
- Four mass flow controllers & four fast-load pumps
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Incubator Bioreactor
- Closed-system single use vessel in 300 mL
- User friendly interface to control agitation & aeration
- Small footprint
- Integrated active pump for BioThrust Membrane Stirrer
ComfyCell Features
Maximum Cell Yield
Low Shear Forces
Low shear forces of integrated Membrane Stirrer both decrease cell destruction as well as increase growth and differentiation speed during cultivation.
Bubble-free Aeration
Bubble-free aeration inhibits the formation of foam. The absence of foam increases working volume & significantly eases the handling of the culture.
Unsurpassed Gas Transfer
Unsurpassed gas transfer efficiency of the Membrane Stirrer (up to 100%) enables higher cell densities that can reduce process duration & media consumption.
Application Agnostic
Slow Rotation Speed
Slow rotation speeds gently hold microcarriers & cell agglomerates of at least 3mm diameter in suspension.
Flexible Working Volume
Flexible working volumes & cell retention filter enable fed-batch & perfusion processes.
Real Scalability
Consistent Mixing Condition
Consistent mixing conditions in scale-up from 250 mL to 200 L due to geometric dimensioning of the vessel & Membrane Stirrer.
Stable Gas Transfer
Stable gas transfer rates across all sizes from 250 mL to 200 L due to proportional growing membrane surface area.
All for Quality & Control
Precise Shear Forces
Precisely controllable shear forces, independent of gas transfer rates.
Continuous CO2 Stripping
Continuous CO2-stripping to achieve unseen product quality due to no CO2 accumulations.
In-Process Control
In-process control for precise & cell-specific management of cultivation parameters.
ComfyCell Product Catalogue
General
| Product Group | Product Type | Product Name |
|---|---|---|
| Benchtop Bioreactors | Controller | BioThrust Controller |
| Reusable Glass Vessel | BioThrust 0.25L Vessel | |
| BioThrust 2L Vessel | ||
| BioThrust 10L Vessel | ||
| Single-Use Vessel | BioThrust 0.3L Vessel | |
| BioThrust 2L Vessel (Coming Soon) | ||
| BioThrust 10L Vessel (Coming Soon) | ||
| Bioreactor for Incubator | Base Unit | BioThrust Incu |
| Single-Use Vessel | BioThrust Incu 0.3L Vessel |
Use Cases
Whether you want to upgrade your established processes or move into 3D cultivation, our wide range of offerings can support you!
Buy or rent our 250mL to 2L bioreactor systems to upgrade your processes or get started with 3D cell cultivation.
Apply our 2L to 50L bioreactor systems to support clinical trials of various sizes efficiently and ensure commercial viability.
Scale up therapies to industrial sizes with our technically verified 50L to 1000L bioreactor systems.
Latest Publications
Experience The Comfycell Platform
Developed to meet your specific need, from reusable to single-use, from lab to commercial scale.
Experience the Comfycell Yourself.
Convince yourself of the new generation of bioreactors - short delivery times, attractive financing models, and process experts by your side make getting started as easy as possible for you.
